Description

(Sterile L-Theanine Injectable for Stress Modulation, Cognitive Support, and Neuroregulation)

Pharmaceutical-Grade L-Theanine for Neuromodulation and Relaxation Without Sedation

Theanine 50 mg/mL – 10 mL is a sterile, preservative-free injectable formulation of L-theanine, an amino acid derived from green tea (Camellia sinensis) that is clinically recognized for its ability to promote calm focus, reduce stress responses, and support cognitive clarity—without causing drowsiness. It is used in functional medicine, nootropic protocols, and IV nutrient therapy as a neuromodulatory compound that can help restore autonomic balance, particularly in individuals under chronic psychological or physiological stress.

By influencing alpha brain wave production, glutamate regulation, and GABA enhancement, L-theanine acts as a natural anxiolytic and cognitive stabilizer, making it an ideal addition to both standalone injection protocols and combinatory IV infusions for brain and mood support.

Product Specifications

• Active Ingredient: L-Theanine

• Concentration: 50 mg/mL

• Total Volume: 10 mL

• Formulation: Sterile aqueous injectable

• Preservative-Free: Suitable for sensitive individuals and frequent dosing

• Route of Administration: Intramuscular (IM) or Intravenous (IV, diluted) under supervision

• Compounded in accordance with USP <797> sterile compounding standards

• Storage: Store refrigerated (2–8°C); protect from light and freezing

What Is L-Theanine?

L-Theanine is a naturally occurring non-dietary amino acid structurally similar to glutamate. Found almost exclusively in tea leaves, it crosses the blood-brain barrier and interacts with neurotransmitter systems to produce a state of relaxed alertness, enhance cognitive performance, and reduce the perception of stress.

Unlike sedatives or stimulants, theanine enhances calmness without impairing function or inducing fatigue, making it ideal for clinical applications targeting stress regulation, anxiety reduction, and focus optimization.

Key Clinical Benefits

1. Stress and Anxiety Reduction

• Promotes alpha brain wave activity, associated with a relaxed mental state

• Modulates the stress response without blunting alertness or cognitive ability

• Often used in patients with generalized anxiety, burnout, or overstimulation

2. Cognitive Enhancement and Focus

• Improves attention span, working memory, and task-switching ability

• Particularly effective when used adjunctively in neuro-cognitive IVs or alongside nootropics

3. Sleep and Circadian Rhythm Support

• Though non-sedating, L-theanine can help reduce sleep latency and improve sleep quality in patients with stress-related insomnia

• Often paired with melatonin, magnesium, or GABAergic agents in sleep protocols

4. Neuroprotection

• Exhibits antioxidant and glutamate-modulating properties that may protect neurons from excitotoxicity

• May be supportive in patients with neurodegenerative concerns, brain fog, or recovering from stress-related cognitive decline

5. Autonomic Nervous System Balance

• Reduces sympathetic dominance and restores parasympathetic tone

• Useful in individuals with chronic HPA axis activation, palpitations, or anxiety-related tachycardia

Clinical Use Cases

• Functional IV nutrient therapy

• Stress modulation protocols

• Nootropic and cognitive enhancement therapy

• Mood support and anxiety treatment

• Adjunct to stimulant-based treatments to reduce jitteriness

• Neuroinflammation and detoxification programs

Dosage and Administration

• Route: Intramuscular (IM) or Intravenous (IV)

• IM Administration: 1–2 mL per dose, 1–3 times weekly

• IV Use: Typically diluted in 100–250 mL of normal saline or D5W

• May be administered alone or combined with complementary agents such as magnesium, taurine, or B vitamins

All injections should be administered by trained medical professionals using sterile technique.

Safety and Tolerability

L-Theanine is extremely well tolerated, with a high safety margin and no known potential for dependence, sedation, or tolerance.

Possible mild side effects may include:

• Temporary lightheadedness

• Mild GI discomfort

• Injection site irritation (rare)

No significant interactions are reported with common medications. Theanine may synergize well with caffeine, magnesium, adaptogens, or B-complex vitamins.

Storage and Handling

• Store at 2–8°C

• Protect from light and freezing

• Use within 28 days of first vial puncture

• Single or multiple-dose vial with sterile access protocol

Ideal For Use In:

• Integrative and functional medicine clinics

• Nutritional IV therapy centers

• Cognitive health and neuro-wellness programs

• Stress reduction and HPA axis recovery plans

• Sleep and mental clarity optimization therapies

Summary

Theanine 50 mg/mL – 10 mL Vial offers a clinically validated solution for reducing stress, enhancing cognition, and restoring autonomic balance in a non-sedating, well-tolerated injectable format. Ideal for standalone injection use or incorporation into IV wellness infusions, this formulation is a powerful tool for modern neuro-supportive care.