Description

(Sterile Vitamin B3 Injectable for Skin Health, Cellular Metabolism, and Anti-Inflammatory Support)

A Targeted, Injectable Form of Vitamin B3 for Metabolic, Neurological, and Dermatological Benefits

Niacinamide (Vitamin B3) 100 mg/mL – 10 mL Vial is a preservative-free, sterile injectable formulation of niacinamide, a water-soluble form of vitamin B3 known for its anti-inflammatory, energy-boosting, and skin-renewing properties. Administered intramuscularly or intravenously under the supervision of a qualified healthcare provider, this formulation offers highly bioavailable niacinamide that supports cellular repair, immune modulation, neurological health, and glucose metabolism.

Niacinamide injections are often used in functional and integrative medicine, dermatology, and metabolic optimization programs to improve vitamin B3 status in patients with absorption issues or increased physiological demand. Unlike niacin (nicotinic acid), niacinamide does not cause flushing, making it a more tolerable and targeted choice for therapeutic applications.

Product Specifications

• Active Ingredient: Niacinamide (Vitamin B3, flush-free form)

• Concentration: 100 mg/mL

• Total Volume: 10 mL multi-dose vial

• Form: Sterile, aqueous solution

• Preservative-Free

• Compounded to USP <797> standards

• Route of Administration: Intramuscular (IM) or Intravenous (IV, diluted)

• Storage: Refrigerate at 2–8°C; protect from light

What Is Niacinamide?

Niacinamide, also known as nicotinamide, is the amide form of niacin (vitamin B3). It is a precursor to NAD+ (nicotinamide adenine dinucleotide) and NADP+, two coenzymes that play crucial roles in:

• Cellular energy production (ATP synthesis)

• DNA repair and gene expression

• Redox homeostasis

• Inflammation control and immune regulation

Unlike nicotinic acid, niacinamide does not cause vasodilation or skin flushing, making it ideal for regular use in patients with sensitivity to traditional niacin supplements.

Key Benefits

1. Cellular Energy and Anti-Aging

• As a precursor to NAD+, niacinamide supports mitochondrial function and reduces oxidative stress.

• Promotes healthy aging, cellular regeneration, and improved skin integrity.

2. Skin Health and Dermatological Uses

• Reduces inflammation, redness, and acne-related lesions

• Improves skin barrier repair, hydration, and texture

• Used in injectable protocols for hyperpigmentation, rosacea, and photoaging

3. Neurological and Cognitive Support

• Enhances neuroprotection through NAD+ dependent repair pathways

• May support cognitive function in individuals with brain fog, fatigue, or mild neurodegeneration

4. Metabolic and Insulin Sensitivity Support

• Plays a role in glucose metabolism, insulin regulation, and reducing inflammatory cytokines

• Used in metabolic programs for insulin resistance, fatty liver, and PCOS adjunct therapy

Clinical Applications

• Chronic fatigue and mitochondrial dysfunction

• Skin rejuvenation protocols and injectable dermatology

• IV nutrient therapy for NAD+ support

• Adjunctive therapy in acne, rosacea, and pigmentation

• Functional medicine protocols for inflammation and stress

Dosage and Administration

• IM Use: Direct intramuscular injection, typically 1–2 mL weekly or biweekly

• IV Use: Always diluted in a compatible carrier fluid such as normal saline
  • Dosage and dilution depend on total formulation of the IV cocktail

  • Common in combination with other B vitamins and amino acids for systemic support

Tolerability and Safety

Niacinamide is generally well tolerated, with a lower risk of adverse effects compared to nicotinic acid.

Potential side effects (rare, usually with high doses):

• Mild headache or dizziness

• Nausea or GI upset

• Injection site discomfort

Contraindications:

• Known hypersensitivity to vitamin B3 or formulation components

• Use caution in patients with active liver disease (monitor liver enzymes during high-dose use)

Storage and Handling

• Store refrigerated at 2–8°C

• Do not freeze

• Use within 28 days of opening

• Use sterile techniques for each draw

Ideal For:

• Dermatology clinics offering injectable skin therapies

• IV therapy centers delivering advanced nutrient infusions

• Functional and integrative medicine practices

• Metabolic and longevity-focused wellness centers

Niacinamide 100 mg/mL – 10 mL is a versatile injectable vitamin B3 formulation offering significant advantages for patients seeking non-flushing metabolic support, skin health optimization, and enhanced cellular energy. Its wide safety margin and potent clinical applications make it an ideal addition to modern IV and injectable nutrient protocols.