Description

(Testosterone Cypionate, USP – Sterile Intramuscular Solution)

High-Concentration, Long-Acting Testosterone Therapy for Clinical TRT Protocols

Empower Testosterone Cypionate Injection 200 mg/mL is a sterile, oil-based intramuscular formulation compounded to support testosterone replacement therapy (TRT) in adult men with clinically diagnosed hypogonadism or testosterone deficiency. Prepared by Empower Pharmacy under USP <797> sterile compounding standards, this product provides bioidentical testosterone in a highly concentrated 5 mL vial for flexible dosing and sustained therapeutic benefit.

Each 5 mL multidose vial contains a total of 1,000 mg of testosterone cypionate, allowing for both standard and advanced TRT regimens. The 200 mg/mL concentration is ideal for patients on higher-dose protocols or those seeking reduced injection volume with extended duration between doses.

Key Features

• High potency: 200 mg/mL concentration

• 5 mL vial provides 1,000 mg of total testosterone

• Suspended in a sterile, pharmaceutical-grade oil

• Allows for weekly, bi-weekly, or microdosed administration

• Trusted for clinical TRT and gender-affirming hormone protocols

• Compounded in a USP-compliant sterile facility

Clinical Applications

This formulation is indicated for the treatment of:

• Primary hypogonadism (e.g., congenital or acquired testicular failure)

• Secondary hypogonadism (e.g., pituitary dysfunction)

• Age-related testosterone decline with symptomatic low-T

• Post-surgical testosterone replacement (e.g., orchiectomy)

• Gender-affirming hormone therapy (FTM transition support)

• Hormone optimization programs in integrative or men’s health clinics

Patients eligible for therapy should demonstrate low serum testosterone levels on laboratory evaluation and exhibit clinical signs such as fatigue, low libido, erectile dysfunction, loss of muscle mass, or mood disturbances.

Mechanism of Action

Testosterone cypionate is a long-acting ester of testosterone. Upon intramuscular injection, it undergoes slow hydrolysis, gradually releasing free testosterone over 7–10 days. This active form binds to androgen receptors in tissues such as muscle, bone, brain, and reproductive organs, where it mediates its physiologic effects.

Therapeutic outcomes include:

• Increased lean muscle mass and strength

• Improved sexual function and libido

• Elevated mood, focus, and energy levels

• Reduced visceral fat and metabolic dysfunction

• Support for bone density and cardiovascular markers

• Improved hematologic and recovery parameters

Dosage and Administration

• Route: Intramuscular (IM) injection

• Typical protocols:
  • 100 mg weekly (0.5 mL)

  • 200 mg every 10–14 days (1.0 mL)

  • 50–70 mg every 3–4 days in microdosing regimens

• Injection site: Gluteal or vastus lateralis muscle

• Rotate sites and use sterile technique for each injection

• May be self-administered with medical training or clinic-assisted

The 5 mL vial provides multiple doses depending on patient-specific protocols, enabling clinicians to fine-tune treatment frequency and titrate doses effectively.

Clinical Benefits

Patients under guided testosterone therapy often report:

• Enhanced physical energy and motivation

• Increased sexual desire and performance

• More stable mood, focus, and cognitive clarity

• Noticeable body composition improvements

• Reduction in fatigue, irritability, and depressive symptoms

• Improved sleep and overall well-being

Most patients begin to feel symptomatic improvement within 3–6 weeks, with full effects typically achieved within 8–12 weeks.

Monitoring and Adjustments

TRT should be managed by a qualified provider with regular monitoring of:

• Total and Free Testosterone

• Estradiol (E2) – to evaluate estrogen conversion

• Hematocrit and Hemoglobin – to prevent erythrocytosis

• Prostate-Specific Antigen (PSA) – for men over 40

• Lipid panel, liver enzymes, SHBG, as indicated

Dose adjustments should be made based on both lab values and patient-reported outcomes.

Safety Information

Common side effects (typically dose-related):

• Acne, oily skin

• Water retention

• Mood variability

• Elevated red blood cell count

• Estrogen-related symptoms (e.g., gynecomastia)

Serious risks (with improper use or lack of monitoring):

• Polycythemia (may increase cardiovascular risk)

• Suppression of natural testosterone production

• Prostate tissue stimulation in older men

Contraindications:

• Prostate or breast cancer in men

• Severe untreated sleep apnea

• History of thromboembolic disorders

• Known hypersensitivity to testosterone or oil carriers

Storage and Handling

• Store at controlled room temperature (59°F to 77°F / 15°C to 25°C)

• Protect from light and heat

• Do not freeze

• Use sterile syringes and needles for each draw

• Discard vial if solution becomes discolored or cloudy

Who It’s For

Empower Testosterone Cypionate 200 mg/mL (5 mL) is designed for:

• Men on long-term TRT needing consistent, high-potency therapy

• Patients preferring less frequent injections with smaller volumes

• FTM patients in maintenance or dose-stabilization phases

• Clinics standardizing weekly or bi-weekly dosing models

• Individuals seeking a convenient, high-yield multidose format

Empower Testosterone Cypionate 200 mg/mL (5 mL) delivers a clean, potent, and customizable option for safe and effective testosterone restoration. Backed by clinical oversight and precise compounding standards, this formulation supports sustained hormone balance, energy, and vitality.