Description

(Dual Growth Hormone Secretagogue Blend for Anti-Aging, Recovery, and Hormone Optimization)

Synergistic Peptide Therapy to Support Growth Hormone Release, Recovery, and Cellular Vitality

Sermorelin and Ipamorelin, combined in a balanced 1:1 ratio at 15 mg each per 10 mL vial, offer a synergistic approach to stimulating endogenous growth hormone (GH) production. This physician-formulated blend harnesses the strengths of both peptides—Sermorelin, a growth hormone-releasing hormone (GHRH) analog, and Ipamorelin, a selective growth hormone secretagogue (GHS)—to mimic the body’s natural GH secretion cycle without suppressing the hypothalamic-pituitary axis.

Designed for subcutaneous injection, this formulation is a core component of many age management, wellness optimization, and performance medicine protocols. It is particularly effective for individuals experiencing age-related decline in GH levels, those recovering from injury or chronic fatigue, and patients seeking improved body composition, sleep, and metabolic function.

Product Details

• Active Ingredients: Sermorelin acetate (15 mg) / Ipamorelin acetate (15 mg)

• Total Volume: 10 mL vial (preserved or preservative-free upon request)

• Concentration: 1.5 mg/mL of each peptide when reconstituted

• Route of Administration: Subcutaneous injection

• Storage (Unreconstituted): Store at room temperature (15–25°C)

• Storage (After Reconstitution): Refrigerate at 2–8°C (36–46°F); use within 30 days

• Use: Compounded peptide therapy for clinical protocols

What Is Sermorelin/Ipamorelin?

Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH 1–29), which stimulates the anterior pituitary to release GH in a controlled, physiologic pulse. Ipamorelin, on the other hand, is a ghrelin mimetic that binds to growth hormone secretagogue receptors (GHS-R1a), triggering a separate GH release pathway.

Together, they amplify GH secretion naturally and safely, mimicking youthful hormone rhythms while avoiding the risks associated with direct hGH (human growth hormone) injections.

Mechanism of Action

Sermorelin works upstream by activating GHRH receptors in the pituitary, increasing the amplitude of GH pulses.
Ipamorelin complements this by acting at ghrelin receptors, enhancing the frequency and consistency of those pulses.

Combined, they:

• Stimulate natural GH and IGF-1 production

• Promote lipolysis and fat metabolism

• Support muscle preservation and recovery

• Enhance deep sleep and circadian rhythm

• Improve collagen synthesis, joint function, and skin tone

This combination provides dual-pathway stimulation of GH with minimal side effects, improved receptor targeting, and no desensitization over standard treatment cycles.

Clinical Applications

1. Anti-Aging and Hormonal Wellness

• Restores youthful GH levels naturally

• Supports skin elasticity, hair quality, and joint integrity

• Improves energy, sleep quality, and mood

2. Athletic Recovery and Muscle Preservation

• Enhances protein synthesis and lean body mass retention

• Speeds post-exercise recovery and reduces injury downtime

3. Fat Loss and Metabolic Optimization

• Promotes visceral fat reduction

• Improves glucose handling and insulin sensitivity

4. Sleep Enhancement

• Increases time spent in deep (slow wave) sleep, improving cognitive and physical regeneration

Dosing and Administration

• Typical dose: 300–500 mcg of each peptide (600–1000 mcg combined), subcutaneously

• Frequency: Once daily at bedtime for maximum GH synchrony

• Protocol length: 8–12 weeks per cycle, with reassessment between cycles

• Reconstitution instructions: Add 10 mL of bacteriostatic water to vial and store refrigerated

All dosing should be customized based on IGF-1 monitoring, body composition goals, and provider guidance.

Safety and Tolerability

Sermorelin/Ipamorelin therapy is well tolerated and non-suppressive to natural GH production. Unlike hGH injections, it does not shut down pituitary function and carries a significantly lower risk of side effects.

Mild side effects may include:

• Redness at injection site

• Temporary water retention or fatigue during early weeks

• Lightheadedness or vivid dreams (usually transient)

No known long-term adverse effects when administered under professional care.

Contraindications and Precautions

Do not use if:

• You have active malignancy (GH may stimulate tumor growth)

• Pregnant or breastfeeding

• Severe untreated hypothyroidism or adrenal dysfunction

Use with caution:

• In individuals with insulin resistance or Type 2 diabetes (monitor glucose control)

• When combining with other GH secretagogues or hormones

Storage Instructions

• Before reconstitution: Store at room temperature

• After reconstitution: Refrigerate between 2–8°C

• Use within 30 days of mixing

• Keep away from light and contamination

Why Choose Sermorelin/Ipamorelin?

• Dual-pathway GH stimulation without suppression

• Safer alternative to hGH therapy

• Supports youthful recovery, lean mass, sleep, and skin health

• Compatible with testosterone, NAD+, and weight loss protocols

• Well-researched with strong patient tolerability

Summary

Sermorelin/Ipamorelin – 15 mg / 15 mg (10 mL Vial) delivers a powerful, physician-trusted solution for restoring natural growth hormone secretion. Whether you’re seeking improved recovery, age-defying vitality, or support through hormonal transitions, this peptide blend offers a balanced, safe, and clinically effective strategy to optimize performance and longevity from the inside out.