Description

(Peptide Therapy for Sexual Function, Libido Enhancement, and Arousal Response)

Advanced Peptide Solution for Sexual Wellness and Desire Regulation

PT-141, also known by its generic name Bremelanotide, is a melanocortin receptor agonist developed to address hypoactive sexual desire disorder (HSDD) and sexual arousal dysfunction in both men and women. Offered as a 20 mg lyophilized peptide vial, this formulation is designed for reconstitution and subcutaneous administration under medical guidance.

Unlike traditional erectile dysfunction (ED) medications that target the vascular system, PT-141 operates through the central nervous system, enhancing libido and sexual responsiveness by acting directly on hypothalamic melanocortin receptors (MC3R and MC4R). It is widely regarded for its ability to initiate sexual desire, intensify arousal, and increase orgasmic potential—especially in individuals with psychological or neurogenic sexual dysfunction.

Product Details

• Active Ingredient: Bremelanotide (PT-141)

• Concentration: 20 mg per vial (lyophilized powder)

• Administration: Subcutaneous injection after reconstitution

• Volume: Reconstituted per provider instruction (typically 1–2 mL bacteriostatic water)

• Use: For clinical and research use under medical supervision

• Storage: Store lyophilized powder at 2–8°C (36–46°F); protect from light

What Is PT-141?

PT-141 is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It was initially investigated as a tanning agent but later gained prominence for its unexpected sexual arousal effects. Unlike phosphodiesterase inhibitors like sildenafil (Viagra), which enhance blood flow to the genitals, PT-141 acts at the neurological level to increase libido, arousal sensitivity, and sexual readiness.

Its benefits apply to both men with erectile dysfunction (ED) and women experiencing low sexual desire (HSDD) due to hormonal changes, psychological stress, or neurological imbalances.

Mechanism of Action

PT-141 works by binding to melanocortin receptors (MC-3 and MC-4) in the central nervous system, particularly within the hypothalamus. This action:

• Activates sexual desire and arousal pathways

• Enhances dopaminergic signaling, promoting motivation and libido

• Induces pro-sexual behaviors and heightened sensitivity to stimulation

• Bypasses reliance on vascular mechanisms (unlike PDE5 inhibitors)

This mechanism allows PT-141 to be effective even in individuals who have no physical issues with blood flow, but experience a lack of desire or arousal.

Clinical Applications

PT-141 is commonly used for:

• Male sexual dysfunction (with or without ED)

• Female sexual arousal disorder (FSAD) and hypoactive sexual desire disorder (HSDD)

• Loss of libido due to menopause, antidepressants, or stress

• Enhancement of sexual confidence and spontaneity

• Adjunct to testosterone therapy or HRT

It has demonstrated success in both pre-menopausal and post-menopausal women, as well as in men who do not fully respond to PDE5 inhibitors.

Dosing and Administration

• Typical dose: 1–2 mg via subcutaneous injection

• Onset: Begins within 30–60 minutes of administration

• Duration of action: 6–12 hours (individual variability may apply)

• Injection sites: Abdomen, thigh, or other subcutaneous regions

Note: Do not exceed one dose in 24 hours. Use is typically limited to no more than 8 doses per month, as per clinical protocols.

Safety and Side Effects

PT-141 is generally well-tolerated, but like all peptide therapies, it can carry mild and transient effects.

Common side effects may include:

• Nausea (especially at higher doses)

• Facial flushing or warmth

• Headache

• Injection site irritation

• Transient increase in blood pressure

These effects are usually mild and resolve within hours. Clinical studies have shown that PT-141 does not cause priapism, hormone imbalance, or cardiovascular suppression.

Contraindications and Precautions

Do not use if:

• You are pregnant, nursing, or trying to conceive

• You have uncontrolled hypertension

• You are hypersensitive to peptide-based therapies

• You have a history of cardiovascular events unless medically cleared

Use caution if:

• You’re on concurrent medications affecting blood pressure or libido

• You have known dopamine dysregulation conditions

• You are using other sexual function medications (e.g., PDE5 inhibitors)

Storage and Handling

• Store lyophilized powder at 2–8°C (36–46°F)

• Once reconstituted, refrigerate and use within 30 days

• Use sterile technique for mixing and withdrawal

• Protect from direct light and avoid contamination

Why Choose PT-141?

• Direct activation of sexual desire centers in the brain

• Works in both men and women, regardless of age or hormonal status

• Non-hormonal, non-anabolic, and non-stimulant

• Enhances natural sexual experience, confidence, and arousal response

• Effective even when traditional therapies fall short

Summary

PT-141 (Bremelanotide) 20 mg Vial offers a revolutionary approach to sexual dysfunction treatment and libido enhancement, especially in cases where traditional medications are ineffective. By working at the level of the brain rather than the blood vessels, PT-141 allows users to rediscover desire, responsiveness, and intimacy naturally. It is a powerful tool in sexual wellness protocols, designed to restore not just function—but pleasure and spontaneity.