Description

Triple-Action Topical Solution for Androgenetic Alopecia and Hormonal Hair Loss

This advanced, prescription-only solution delivers a synergistic blend of three clinically validated active agents—Minoxidil, Tretinoin, and Spironolactone—designed to treat androgenetic alopecia (AGA) and hormonal hair thinning in both men and women. Formulated in a fast-absorbing, non-greasy base, this product is intended for localized application to thinning areas of the scalp, providing targeted stimulation, hormonal regulation, and enhanced follicular uptake.

Ideal for patients who have plateaued on standard Minoxidil therapy or who exhibit signs of hormone-driven miniaturization, this formulation addresses the vascular, hormonal, and cellular turnover aspects of hair loss—offering a comprehensive approach in a single topical application.

Key Benefits

• Stimulates hair regrowth by prolonging the anagen phase 
• Enhances follicular absorption with increased skin turnover 
• Blocks androgen receptors locally to reduce DHT sensitivity 
• Targets multiple causes of thinning, including hormonal imbalance and follicular dormancy 
• Non-oily formula dries quickly and integrates well into existing regimens 
• Suitable for men and women under professional supervision 

Active Ingredients & Mechanism of Action

Minoxidil 70 mg
Minoxidil acts as a potent vasodilator, increasing blood flow to the scalp and revitalizing shrunken hair follicles. It prolongs the growth (anagen) phase, enlarges follicle diameter, and increases the number of hairs in active growth. The 70 mg strength is tailored for optimal effectiveness in localized application zones, providing enhanced stimulation without systemic effects.

Tretinoin 1.25 mg
Tretinoin (all-trans retinoic acid) works by increasing epidermal turnover, unclogging hair follicles, and improving the penetration of other active ingredients—especially Minoxidil. It also helps regulate sebum production, which can be beneficial for individuals with oily or buildup-prone scalps.

Spironolactone 5 mg
Topical Spironolactone acts as a local anti-androgen, blocking the effects of dihydrotestosterone (DHT) at the follicular level. This reduces androgen-related miniaturization without systemic hormonal disruption. Especially useful in female pattern hair loss, Spironolactone helps stabilize shedding and supports regrowth in hormone-sensitive scalp zones.

Indications

This triple-action topical solution is indicated for:

• Androgenetic alopecia (male or female pattern hair loss) 
• Hormonal scalp thinning in women (frontal fibrosing, diffuse AGA) 
• Post-menopausal or PCOS-related hair loss 
• Thinning unresponsive to Minoxidil monotherapy 
• Patients avoiding oral anti-androgens or finasteride 
• Adjunctive care alongside PRP, hair transplant, or oral therapies 

It is designed for once-daily use and should be applied under the guidance of a healthcare provider.

Directions for Use

1. Ensure the scalp is clean and dry. 
2. Using the provided dropper, apply 1 mL of solution to the affected scalp area once daily. 
3. Spread evenly using fingertips or a massaging tool. 
4. Do not rinse. Allow to absorb fully before applying other hair or scalp products. 
5. Wash hands after application. 

Consistent use is critical. Visible results typically appear after 3–6 months of daily application.

What to Expect

• Weeks 1–4: Reduced scalp inflammation, normalized oil production 
• Weeks 4–8: Stabilization of shedding, improved scalp texture 
• Months 2–4: Early regrowth, thickening of miniaturized hair shafts 
• Months 5–6+: Increased density, improved volume and hairline coverage 

Initial shedding may occur due to follicular cycling and is typically temporary.

Safety & Precautions

• For external use only 
• Avoid contact with eyes, mucous membranes, or irritated skin 
• Not recommended during pregnancy or breastfeeding 
• Discontinue use if persistent redness, peeling, or irritation occurs 
• Consult your physician if using other hormonal or dermatologic treatments 

Mild dryness or peeling may occur in the first 2–3 weeks due to Tretinoin. This often resolves with continued use or application of a gentle scalp moisturizer.

Storage Instructions

• Store at 15–25°C (59–77°F) 
• Keep away from direct heat, light, and moisture 
• Use within 90 days of opening 
• Keep out of reach of children 

Who Should Use This Product?

This solution is ideal for:

• Men and women with early to moderate androgenetic alopecia 
• Female patients with hormonal hair thinning due to PCOS, menopause, or contraceptive use 
• Individuals sensitive to oral anti-androgens or who prefer localized therapy 
• Patients looking to enhance efficacy beyond traditional Minoxidil formulations 
• Users seeking targeted follicular support with anti-DHT activity 

A Multi-Mechanism, Precision-Targeted Regrowth Formula

The Minoxidil / Tretinoin / Spironolactone topical solution is a next-generation approach to hair loss management, combining vascular stimulation, hormonal modulation, and enhanced dermal penetration in a single, easy-to-use formula. By delivering treatment exactly where it’s needed, this serum helps restore density, texture, and follicular activity—offering a powerful tool in the management of complex or resistant hair loss cases.