Description

(Dual-Action Topical Relief for Hemorrhoid-Associated Inflammation and Discomfort)

Extended-Use Topical Therapy for Hemorrhoidal Swelling, Itch, and Irritation

This 60-gram compounded Hemorrhoid Preparation Ointment combines Hydrocortisone 2.5%, a potent topical corticosteroid, and Pramoxine 1%, a fast-acting local anesthetic, into a single, effective formulation for the treatment of internal and external hemorrhoidal symptoms. Designed for both acute flare-ups and longer-term symptom control, this prescription ointment is widely used in colorectal, primary care, and gastrointestinal practices.

The extended volume (60g) is ideal for patients managing recurrent inflammation, post-surgical sensitivity, or maintenance care, allowing for a complete course of therapy without frequent refills.

Product Overview

• Active Ingredients:
  • Hydrocortisone 2.5% – Corticosteroid for reducing inflammation, swelling, and irritation

  • Pramoxine 1% – Local anesthetic for immediate relief from burning and itching

• Form: Smooth, mucosa-safe ointment suitable for external or intrarectal use

• Packaging: 60 grams per container (jar or tube)

• Use: Topical rectal/perianal application, as prescribed

• Storage: Room temperature (68–77°F / 20–25°C); avoid heat or moisture

• Availability: Prescription-only; pharmacist-compounded

Mechanism of Action

Hydrocortisone 2.5% – Corticosteroid Anti-Inflammatory

Hydrocortisone is a topical steroid that acts on the local immune system by inhibiting inflammatory mediators like prostaglandins, leukotrienes, and cytokines. This reduces:

• Perianal redness

• Swelling and pain

• Discomfort related to inflammation during bowel movements

It is particularly effective in relieving mild to moderate internal and external hemorrhoidal inflammation and perianal dermatitis.

Pramoxine 1% – Local Anesthetic for Fast Relief

Pramoxine is a non-narcotic anesthetic that blocks the transmission of nerve signals at the skin’s surface by inhibiting sodium channels. It offers quick symptom relief without systemic absorption or drowsiness.

It is ideal for:

• Soothing itch and burning sensations

• Reducing the urge to scratch, which can exacerbate inflammation

• Increasing comfort post-defecation

Clinical Applications

This formulation is commonly used for:

• Symptomatic relief of hemorrhoids (internal/external)

• Post-hemorrhoid procedure care

• Anal irritation or pruritus ani

• Inflammation due to skin breakdown or friction

• Supportive care in anorectal conditions such as fissures or dermatitis

It may also be used in conjunction with lifestyle interventions, including fiber supplementation and sitz baths.

Dosing & Instructions for Use

• Application frequency: Apply a small, thin layer to the affected area up to 3 times daily, ideally after bowel movements and before bed

• External use: Gently massage into clean, dry skin around the anal area

• Internal use: If advised by your provider, use an applicator or gloved finger to apply a small amount into the anal canal

• Course duration: Typically 5–14 days; extended use should be monitored to avoid skin thinning

Avoid using in combination with other topical corticosteroids unless directed by your healthcare provider.

Safety and Tolerability

Hydrocortisone 2.5% / Pramoxine 1% is well tolerated, particularly for localized, short- to mid-term use.

Mild side effects may include:

• Temporary stinging or mild dryness

• Skin irritation if applied to raw or broken tissue

• Rare hypersensitivity or allergic reaction (discontinue and consult provider)

Long-term use of topical corticosteroids may lead to skin thinning (atrophy), so ongoing supervision is recommended for extended courses.

Contraindications

Do not use this ointment if:

• You are allergic to hydrocortisone, pramoxine, or similar compounds

• The area has an active fungal, viral, or bacterial infection (unless concurrently treated)

• You are pregnant or breastfeeding, unless prescribed by your physician

• You are using other steroid-containing preparations in the same area without coordination

Storage and Handling

• Store at room temperature (20–25°C)

• Do not freeze

• Replace cap tightly after each use

• Keep out of reach of children

• Follow pharmacy-labeled beyond-use date (BUD) and usage guidelines

Why Choose This Compounded Hemorrhoid Prep?

• Dual-action formula addresses both cause (inflammation) and symptom (discomfort)

• Non-systemic and safe for localized application

• Provides a steroid + anesthetic combination not found in many over-the-counter treatments

• Suitable for recurrent users, post-surgical patients, or those needing extended coverage

• Customized compounding ensures consistency, purity, and clinical efficacy

Summary

Hemorrhoid Prep – Hydrocortisone 2.5% / Pramoxine 1% Ointment (60g) offers comprehensive relief for hemorrhoidal symptoms through a physician-recommended, pharmacist-compounded formulation. With anti-inflammatory and anesthetic properties in one topical base, this preparation delivers targeted comfort and therapeutic healing, supporting both short-term flare-ups and longer courses of symptom management in hemorrhoid care.