Description

(Sterile Intramuscular Solution | Testosterone Cypionate, USP)

Precision-Dosed, Long-Acting Testosterone Therapy for Hormone Optimization and Hypogonadism Management

Empower Testosterone Cypionate Injection 100 mg/mL is a sterile, preservative-free, compounded intramuscular solution designed to deliver reliable and consistent testosterone replacement therapy (TRT) in adult males with clinically diagnosed hypogonadism or testosterone deficiency.

Manufactured by Empower Pharmacy, this 5 mL multi-use vial provides a total of 500 mg of testosterone cypionate, suspended in a pharmaceutical-grade oil base. The 100 mg/mL concentration offers a balanced solution for patients seeking moderate dosing flexibility—enabling both once-weekly and bi-weekly injection schedules, or customized microdosing plans under clinical supervision.

Key Features

• 100 mg/mL strength: ideal for accurate, moderate-dose TRT administration

• Supplied in a 5 mL sterile multidose vial (500 mg total content)

• Bioidentical testosterone cypionate in a high-purity, oil-based carrier

• Supports energy, libido, strength, cognition, and body composition

• Compounded in compliance with USP <797> sterile standards

• Trusted by hormone therapy providers for individualized TRT protocols

Clinical Indications

Testosterone Cypionate Injection is indicated for:

• Primary hypogonadism (e.g., congenital or acquired testicular failure)

• Secondary hypogonadism (e.g., pituitary or hypothalamic dysfunction)

• Age-related testosterone decline with symptomatic presentation

• Androgen deficiency of chronic illness origin

• Transgender hormone therapy (FTM transition protocols)

• Medically guided testosterone optimization in wellness-focused men’s health clinics

TRT is only indicated in men with low serum testosterone levels confirmed by laboratory evaluation, accompanied by clinical symptoms such as fatigue, reduced libido, erectile dysfunction, decreased muscle mass, mood instability, or cognitive decline.

Mechanism of Action

Testosterone cypionate is a long-acting ester of testosterone. Once administered intramuscularly, the ester is slowly hydrolyzed, releasing free testosterone into the bloodstream over 7 to 10 days. The active hormone binds to androgen receptors in tissues such as skeletal muscle, bone, brain, and reproductive organs, initiating anabolic and metabolic functions.

Therapeutic effects include:

• Enhanced protein synthesis and muscle growth

• Increased red blood cell production

• Regulation of mood, mental clarity, and sleep

• Improvement in libido, erectile function, and physical stamina

• Reduction in body fat and insulin resistance

• Support for bone mineral density

Dosage and Administration

• Route: Intramuscular (IM) injection

• Frequency: Common dosing schedules include:
  • 100 mg once weekly

  • 50 mg twice weekly

  • 75 mg every 5 days (in microdosing protocols)

• Volume: At 100 mg/mL, a 100 mg dose equals 1.0 mL injection

• Injection Site: Gluteal or vastus lateralis muscle

• Rotate sites regularly to minimize irritation or scar tissue development

• Injection should be performed under the guidance of a qualified provider or via self-administration after training

The 5 mL vial provides sufficient volume for 5 weekly 100 mg doses, 10 doses at 50 mg, or customized regimens as determined by the prescribing physician.

Monitoring Requirements

To ensure safety and optimize outcomes, regular labs should be performed:

• Total and Free Testosterone (baseline and ongoing)

• Estradiol (E2) – to monitor aromatization levels

• Hematocrit & Hemoglobin – to monitor for polycythemia

• PSA (Prostate Specific Antigen) – for men over 40

• Liver function, lipid profile, and SHBG as clinically appropriate

Safety Profile

Common side effects may include:

• Acne or oily skin

• Increased facial/body hair growth

• Water retention or transient weight gain

• Mood changes or irritability

• Elevated hematocrit (requires monitoring)

Serious risks (with excessive or mismanaged dosing):

• Gynecomastia (due to estradiol conversion)

• Polycythemia (elevated RBC count)

• Prostate enlargement or stimulation (rare in properly managed protocols)

Contraindications

• Known or suspected prostate or breast cancer in males

• History of polycythemia vera

• Severe, untreated obstructive sleep apnea

• Known hypersensitivity to testosterone cypionate or carrier oils

Use caution in patients with cardiovascular disease, hepatic impairment, or thromboembolic risk factors.

Storage and Handling

• Store at 15°C to 25°C (59°F to 77°F)

• Protect from light and extreme temperatures

• Do not freeze

• Use sterile technique for every draw

• Keep out of reach of children

Ideal Candidates

This formulation is ideal for:

• Men initiating TRT with moderate dosing requirements

• Patients seeking a once-weekly or split-dose regimen

• Clinics that offer personalized TRT titration plans

• FTM transition patients in dose-building phases

• Individuals using microdosing strategies to reduce side effects and hormonal peaks

Empower Testosterone Cypionate 100 mg/mL (5 mL vial) offers a stable, controlled, and physician-trusted solution for restoring testosterone to healthy, functional levels—empowering patients to regain energy, confidence, and long-term health.